โ Scribed by Vera Novak; A.M. Abduljalil; P. Novak; P.M. Robitaille
No coin nor oath required. For personal study only.
Ultrahigh-field mri at 8 t offers unprecedented resolution for imaging brain structures and microvasculature.
The aim of this study is to apply high-resolution mri for stroke imaging and to characterize findings at 1.5 and 8 t.
Seventeen subjects with minor ischemic infarcts were studied using t2-weighted gradient echo (ge) and rapid acquisition with relaxation enhancement (rare) images at 8 t with resolution up to 200 microm. in 10 subjects, t1- and t2-weighted fast spin echo (fse) and fluid-attenuated inversion recovery (flair) images were also acquired at 1.5-t mri.
The 8-t images showed infarcts as sharply demarcated areas of high-signal intensity (n=21) and revealed more infarctions than 1.5-t images (n=14) (p<.003). the low-signal intensity areas that surrounded infarctions were suggestive of hemosiderin deposits. the 8-t characteristics of microvessels terminating within the infractions were distinct from normal vasculature. the 8-t images revealed an angioma at the site of a second stroke, not apparent on 1.5-t images.
Ultrahigh-field mri at 8 t is feasible for stroke imaging. the 8-t mri visualized infarcts and microvasculature with high resolution, revealing infarcts and vascular pathologies that were not apparent at 1.5 t.
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