High-resolution simulations of clump–clump collisions using SPH with particle splitting

The rapid detection and identification o

The rapid detection and identification of the impurities of simvastatin using high resolution sub 2 μm particle LC coupled to hybrid quadrupole time of flight MS operating with alternating high–low collision energy

✍ Robert S. Plumb; Michael D. Jones; Paul Rainville; Jose M. Castro-Perez 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 760 KB

## Abstract The profiling and identification of impurities in raw pharmaceuticals or finished drug product is an essential part of the pharmaceutical manufacturing process. Critical to this process is the ability to confirm known, expected impurities and identify new impurities. LC coupled to elect