The objective of this study was to develop and verify a new technique for monitoring the progression of osteoarthritis (OA) by combining a rat model with the imaging modality optical coherence tomography (OCT). Time-sequential, in vivo, OCT imaging was performed on the left femoral condyles of 12 Wi
High resolution, short echo time sodium imaging of articular cartilage
✍ Scribed by E. K. Insko; Ravinder Reddy; J. S. Leigh
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 685 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The sodium present in articular cartilage interacts with the negatively charged proteoglycan aggregates in the matrix of the cartilage. Sodium images of short echo time may be useful for detecting changes that occur in the proteoglycan content of the cartilage. Such changes are indicative of early osteoarthritic damage, for example. Using an asymmetric short echo technique, sodium images of high resolution and signal‐to‐noise ratio that demonstrate anatomic features of the cartilage are presented. These images were obtained with echo times as short as 1 msec, at an inplane resolution of 39 microns by 117 microns and signal‐to‐noise ratios of up to 40:1.
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