High-resolution real-time spiral MRI for guiding vascular interventions in a rabbit model at 1.5T
✍ Scribed by Masahiro Terashima; MinSu Hyon; Erasmo de la Pena-Almaguer; Phillip C. Yang; Bob S. Hu; Krishna S. Nayak; John M. Pauly; Michael V. McConnell
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 127 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To study the feasibility of a combined high spatial and temporal resolution real‐time spiral MRI sequence for guiding coronary‐sized vascular interventions.
Materials and Methods
Eight New Zealand White rabbits (four normal and four with a surgically‐created stenosis in the abdominal aorta) were studied. A real‐time interactive spiral MRI sequence combining 1.1 × 1.1 mm^2^ in‐plane resolution and 189‐msec total image acquisition time was used to image all phases of an interventional procedure (i.e., guidewire placement, balloon angioplasty, and stenting) in the rabbit aorta using coronary‐sized devices on a 1.5 T MRI system.
Results
Real‐time spiral MRI identified all rabbit aortic stenoses and provided high‐temporal‐resolution visualization of guidewires crossing the stenoses in all animals. Angioplasty balloon dilatation and deployment of coronary‐sized copper stents in the rabbit aorta were also successfully imaged by real‐time spiral MRI.
Conclusion
Combining high spatial and temporal resolution with spiral MRI allows real‐time MR‐guided vascular intervention using coronary‐sized devices in a rabbit model. This is a promising approach for guiding coronary interventions. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.