𝔖 Bobbio Scriptorium
✦   LIBER   ✦

High-resolution NMR correlation experiments in a single measurement (HR-PANACEA)

✍ Scribed by Ēriks Kupče; Ray Freeman

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
195 KB
Volume
48
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Three important NMR pulse sequences, INADEQUATE, HSQC and three‐dimensional HMBC have been combined into a single entity called high‐resolution Parallel Acquisition NMR: an All‐in‐one Combination of Experimental Applications (HR‐PANACEA) to provide reliable structural information about a small molecule in a single measurement. This exploits a recent instrumental development that permits simultaneous acquisition of signals from several nuclear species, using multiple receivers. Where high‐precision values of the long‐range heteronuclear splittings are important, selected regions of a large experimental data matrix are extracted and examined with the highest possible resolution. The J‐doubling technique is then applied to derive precise values for these couplings. As proof of principle, the method is applied to the molecule of methyl salicylate, confirming the expected conformation of the COH moiety. Copyright © 2010 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Group assignment and carbon and proton s
Group assignment and carbon and proton shift measurement by heteronuclear zero-quantum carbon-shift correlated 2D NMR in a single experiment
✍ Huldrych Egli; Walter Graf 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 469 KB

A two-dimensional heteronuclear multiple-quantum NMR experiment, based on the DEPT pulse sequence, for the simultaneous determination of the nature of proton-bearing chemical groups together with the measurement and correlation of carbon and proton chemical shifts is presented. Time and computer mem

High-resolution NMR experiments which us
High-resolution NMR experiments which use frequency-selective R.F. Pulses in combination with magnetic field gradients
✍ Michael A. Bernstein; Laird A. Trimble 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

## Abstract Magnetic field gradients were incorporated into the selective COSY experiment. The new gradient‐selected experiment has the expected advantages of significantly improved spectral quality resulting from better artifact suppression and the capacity to acquire spectra using fewer scans. A