## Abstract Understanding the genes and genetic pathways targeted by recurrent chromosomal imbalances in malignancy, along with the molecular mechanisms that generate the imbalances, are important problems in cancer biology. In this report, we demonstrate that oligonucleotide array CGH (oaCGH) anal
High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array
β Scribed by Hiroshi Hayashi; Genta Nagae; Shuichi Tsutsumi; Kiyofumi Kaneshiro; Takazumi Kozaki; Atsushi Kaneda; Hajime Sugisaki; Hiroyuki Aburatani
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 582 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We used arrayβbased comparative genomic hybridization (aCGH) to measure genomic copy number alterations (CNAs) in 42 neuroblastoma cell lines with known 1p36.3, 2p24 (__MYCN__), 11q23, and 17q23 allelic status. All cell lines showed CNAs, with an average of 22.0% of the genome of each s
## Communicated by John McVey Beckwith Wiedemann syndrome (BWS) and Russell Silver syndrome (RS) are growth disorders with opposing epimutations affecting the H19/IGF2 imprinting center at 11p15.5. Overgrowth and tumor risk in BWS is caused by aberrant expression of the paternally expressed, impri
## Abstract Neurofibromatosis Type I (NF1) is an autosomal dominant disorder characterized by the development of both benign and malignant tumors. The lifetime risk for developing a malignant peripheral nerve sheath tumor (MPNST) in NF1 patients is βΌ10% with poor survival rates. To date, the molecu
## Abstract Chronic myelogenous leukemia (CML) evolves from an indolent chronic phase (CP) characterized by the Philadelphia chromosome. Without effective therapy, it progresses to an accelerated phase (AP) and eventually to a fatal blast crisis (BC). To identify the genes involved in stage progres