High-resolution ion isolation with the ion cyclotron resonance capacitively coupled open cell

✍ Scribed by Peter B. O'Connor; Fred W. McLafferty

• Book ID: 103996805
• Publisher: Elsevier Science
• Year: 1995
• Tongue: English
• Weight: 314 KB
• Volume: 6
• Category: Article
• ISSN: 1044-0305
• DOI: 10.1016/1044-0305(95)00232-3

✦ Synopsis

For ion cyclotron resonance, a capacitively coupled open cell variant with fourfold radial symmetry was constructed and tested for axial excitation-ejection of large ions at high resolution. With a reverse of frequency sweep direction, this cell gave substantial improvements in signal-to-noise ratio due to linearization of the excitation electric field. Single isotopic peaks of ubiquitin (8.6-kDa) and carbonic anhydrase (29-kDa) molecular ions could be isolated by selective stored waveform inverse Fourier transform excitation, which yielded an order of magnitude higher isolation resolving power than previously achieved at high mass-to-charge ratio values.