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High-resolution cDNA microarray-based comparative genomic hybridization analysis in neuroblastoma

✍ Scribed by Qing-Rong Chen; Sven Bilke; Javed Khan

Book ID: 116333570
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 676 KB
Volume: 228
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2004.12.056

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## Abstract Deletion of chromosome arm 1p is one of the most frequent genetic alterations in neuroblastoma. However, using conventional comparative genomic hybridization, we have observed amplifications on 1p in 2 neuroblastoma tumors at bands 1p34.2 and 1p36.3, respectively. Using a medium‐resolut