𝔖 Bobbio Scriptorium
✦   LIBER   ✦

High relative frequency of thyroid papillary carcinoma in northern portugal

✍ Scribed by Maria C. Sambade; Vicente S. Goncalves; Manuel Dias; Manuel A. Sobrinho-Simòes

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
586 KB
Volume
51
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

✦ Synopsis

Two hundred and twelve papillary and 40 follicular carcinomas were found in 3002 thyroid glands examined from 1931 to 1975 in four Laboratories of Pathology that fairly cover northern Portugal. There was a striking preponderance of women both in papillary (fema1e:male = 6.9:l) and follicular carcinoma (5.7:l). Sex-specific frequency of malignancy was significantly greater in men (13.3%) than in women (8.8%). The overall papillary/follicular ratio was 5.3:1 and did not significantly change throughout the study period. Papillary/follicular ratio was not significantly greater in litoral (5.51) than in regions with a low iodine intake and a relatively high prevalence of goiter (3.51). It is advanced that this high relative frequency of papillary carcinoma in northern Portugal, even in goiter areas, may reflect the existence of a racial factor since there is not enough evidence to support the influence of dietary iodine, previous irradiation and concurrent thyroiditis.

📜 SIMILAR VOLUMES

Distinct frequency of ret rearrangements
Distinct frequency of ret rearrangements in papillary thyroid carcinomas of children and adults from Belarus
✍ Jan Smida; Konstadinos Salassidis; Ludwig Hieber; Horst Zitzelsberger; Albrecht 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 158 KB

Rearrangements of the ret oncogene were investigated in papillary thyroid carcinomas (PTC) from 51 Belarussian children with a mean age of 3 years at the time of the Chernobyl radiation accident. For comparison, 16 PTC from exposed Belarussian adults and 16 PTC from German patients without radiation

High prevalence of BRAF mutation in a Br
High prevalence of BRAF mutation in a Brazilian cohort of patients with sporadic papillary thyroid carcinomas : Correlation with more aggressive phenotype and decreased expression of iodide-metabolizing genes
✍ Gisele Oler; Janete M. Cerutti 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

## Abstract ## BACKGROUND: Although several studies undoubtedly demonstrated that __BRAF__ mutation is an important genetic event in the pathogenesis of papillary thyroid carcinoma (PTC), its prognostic significance and correlation with less differentiated states remains unclear. It has been sugge