High recombination between the breakpoint of a reciprocal translocation in rye (Secale cerealeL.) and an interstitially located gene

Localization of the 17q breakpoint of a

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients

✍ Nadine Van Roy; Jo Vandesompele; Geert Berx; Katrien Staes; Mireille Van Gele; E 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

## Abstract We have constructed a 1.4‐Mb P1 artificial chromosome/bacterial artificial chromosome (PAC/BAC) contig spanning the 17q breakpoint of a constitutional translocation t(1;17)(p36.2;q11.2) in a patient with neuroblastoma. Three 17q breakpoint‐overlapping cosmids were identified and sequenc