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High production of catalase in hydrogen peroxide-resistant human leukemia HL-60 cell lines

✍ Scribed by Isao Kasugai; Michiyuki Yamada

Book ID: 113239654
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 937 KB
Volume: 16
Category: Article
ISSN: 0145-2126
DOI: 10.1016/0145-2126(92)90129-u

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## Abstract HL‐60‐R, a multi‐drug‐resistant (MDR) subclone of the human leukemia cell line HL‐60, was selected in continuous culture in doxorubicin (DOX) in the absence of mutagenic agents. When compared to the parent line HL‐60, HL‐60‐R showed greater relative resistance to vinblastine than to eto