Previous studies from Spain, Italy, and France have demonstrated a high prevalence (71% to 91%) of antibodies against hepatitis C virus in patients with porphyria cutanea tarda (PCT). To determine the role of hepatitis C virus (HCV) in PCT in Germany, we have assessed the prevalence of antibodies ag
High prevalence of hepatitis C virus infection in Japanese patients with porphyria cutanea tarda
β Scribed by M Kondo; Y Horie; J Okano; A Kitamura; N Maeda; H Kawasaki; S Mishiro; S Yamamoto; T Itou; S Saeki; S Tanaka; H Okamoto
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 129 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0270-9139
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Porphyria cutanea tarda (PCT) is caused by a decreased activity of the hepatic enzyme uroporphyrinogen decarboxylase (URO-D). This deficiency causes overproduction, hepatic deposition, and increased excretion of uroporphyrin. Iron overload and hepatic viral infections are considered aggravating fact
Sporadic porphyria cutanea tarda (PCT) is caused by a reduced activity of uroporphyrinogen decarboxylase (URO-D) in the liver. Mild to moderate iron overload is common in PCT, as iron is one of the factors which trigger the clinical manifestations of the disease through the inactivation of URO-D. A
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