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High pressure: A promising tool for multicomponent reactions

✍ Scribed by Leon W. A. van Berkom; George J. T. Kuster; Hans W. Scheeren

Book ID
111600707
Publisher
Springer
Year
2000
Tongue
English
Weight
153 KB
Volume
6
Category
Article
ISSN
1381-1991

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## Abstract For the first time, uncatalyzed, high‐pressure (0.6β€…GPa) reactions with ketones have proven to be a powerful way to perform the three‐component __Strecker__ synthesis of __Ξ±__‐amino nitriles in high yields. Two types of double __Strecker__ reactions were achieved, but attempts to perfor