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High population incidence of the 15p marker D15Z1 mapping to the short arm of one homologue 14

✍ Scribed by K. Stergianou; C. P. Gould; J. J. Waters; M. Hultén

Book ID: 104659602
Publisher: Springer
Year: 1992
Tongue: English
Weight: 243 KB
Volume: 88
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00197281

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✦ Synopsis

We have read with interest the paper by Smeets et al. (1991), reporting a "Frequent occurrence of translocation of the short arm of chromosome 15 to other D-group chromosomes". We have performed a similar population study of 100 subjects using the satellite-III probe D15Z1 obtained from the same source (Higgins et al. 1985), which is in fact a repetitive human 1.8 kb KpnI sequence and not an alphoid sequence. Under high stringency conditions, this probe has previously been thought to map

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