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High-performance liquid chromatography with chemiluminescence detection of derivatized microcystins

✍ Scribed by Hideaki Murata; Hiroko Shoji; Motoji Oshikata; Ken-Ichi Harada; Makoto Suzuki; Fumio Kondo; Hideko Goto


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
535 KB
Volume
693
Category
Article
ISSN
1873-3778

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Microcystins are potent hepatotoxins produced by cyanobacteria, and are also tumor promoters as well as potent inhibitors of the catalytic subunits of protein phosphatases 1 and 2A. In order to establish a physicochemical method for individual detection and determination of trace amounts of microcys