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High-performance liquid chromatography of mexiletine in plasma

✍ Scribed by M.C.Contreras De Condado; A.Quintana De Gainzarain; I.Mendoza Mujica; J.A.Condado Rodriguez

Book ID
108448301
Publisher
Elsevier Science
Year
1990
Weight
325 KB
Volume
530
Category
Article
ISSN
0378-4347

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A sensitive high-performance liquid chromatographic method with electro-chemical detection is developed for the determination of deacetylmetipranolol (DMP), an active metabolite of beta-sympatholytic drug metipranolol (MP). DMP is extracted from the plasma after basifying with dichloromethane. After