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High-performance liquid chromatographic method for the determination of diltiazem and two of its metabolises in human plasma: application to a new sustained release formulation

โœ Scribed by S. Boucher; F. Varin; Y. Theoret; P. Du Souicht; G. Caille

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
310 KB
Volume
7
Category
Article
ISSN
0731-7085

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A simple and sensitive reversed-phase liquid chromatographic method has been developed and validated for the analysis of nicardipine in human plasma and the study of the pharmacokinetics of the drug in human body. Nicardipine and nimodipine (internal standard) in plasma were extracted with hexane-bu