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High-performance liquid chromatographic method for the determination of dasatinib in rabbit plasma using fluorescence detection and its application to a pharmacokinetic study

✍ Scribed by Kassem, Mohammed G.; Ezzeldin, Essam; Korashy, Hesham M.; Mostafa, Gamal A.E.


Book ID
121775876
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
767 KB
Volume
939
Category
Article
ISSN
1873-376X

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A simple and sensitive reversed-phase liquid chromatographic method has been developed and validated for the analysis of nicardipine in human plasma and the study of the pharmacokinetics of the drug in human body. Nicardipine and nimodipine (internal standard) in plasma were extracted with hexane-bu