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High-performance liquid chromatographic determination of diltiazem and two of its metabolites in plasma using a short alkyl chain silanol deactivated column

✍ Scribed by David R. Rutledge; Ashraf H. Abadi; Larry M. Lopez; Charles A. Beaudreau


Book ID
103804637
Publisher
Elsevier Science
Year
1993
Weight
542 KB
Volume
615
Category
Article
ISSN
0378-4347

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Stability study of diltiazem and two of
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KEY WORDS Diltiazem Stability Plasma HPLC assay INTRODUCTION Diltiazem is a calcium antagonist which is currently used in the treatment of angina pectoris, hypertension, and supraventricular arrhythmias.'-4 At present, in our laboratory, diltiazem and six of its metabolites have been identified and