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High-performance liquid chromatographic determination of amphotericin B in human serum

✍ Scribed by C. Brassinne; C. Laduron; A. Coune; J.P. Sculier; C. Hollaert; N. Collette; F. Meunier


Publisher
Elsevier Science
Year
1987
Weight
441 KB
Volume
419
Category
Article
ISSN
0378-4347

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Improved high-performance liquid chromat
✍ Hideo Hosotsubo; Kikumi Hosotsubo πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 English βš– 347 KB

An improved reversed-phase high-performance liquid chromatographic procedure is described for the determination of Amphotericin B (AMB) in human serum and plasma. The procedure involves the addition of the internal standard, p-nitroaniline, to the sample (0.1 ml) followed by protein precipitation wi