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High-performance liquid chromatographic assay of pyrimethamine, sulfadoxine and its N4-acetyl metabolite in serum and urine after ingestion of suldox

โœ Scribed by Carsten Midskov


Publisher
Elsevier Science
Year
1984
Weight
557 KB
Volume
308
Category
Article
ISSN
0378-4347

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A stereoselective direct liquid chromatographic method for assay of the enantiomers of the โค-adrenergic blocker acebutolol (AC) and its active metabolite, diacetolol (DC), in human serum was developed. The assay is based on extraction with ethyl acetate and separation of enantiomers on an amylose tr