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High performance liquid chromatographic assay of a new fluoroquinolone, LB20304, in the plasma of rats and dogs

โœ Scribed by Mi-Kyeong Seo; Yi-Na Jeong; Hoon-Joo Kim; In-Chull Kim; Yong-Hee Lee

Book ID
112963093
Publisher
Springer
Year
1996
Tongue
English
Weight
357 KB
Volume
19
Category
Article
ISSN
0253-6269

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High-performance liquid chromatographic
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โœ Elsbeth Brunt; Jobst Limberg; Hartmut Derendorf ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 442 KB

A rapid technique for sample preparation and HPLC was developed to study in vitro the erythrocyte binding and plasma protein binding of fleroxacin in the concentration range 0.2-15 micrograms ml-1. The red blood cell partition coefficient of fleroxacin was 1.45 +/- 0.18 at 25 degrees C and was indep