High-performance liquid chromatographic
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J.Scott Eadie; Lincoln J. McBride; J.William Efcavitch; Louis B. Hoff; Richard C
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Article
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1987
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Elsevier Science
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English
โ 893 KB
A significantly improved method for base composition analysis of synthetic oligodeoxyribonucleotides is presented. This highly accurate and sensitive method uses enzymatic digestion followed by high-resolution HPLC of the nucleosides to determine the empirical base composition of the parent compound