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High Performance Computational Methods for Biological Sequence Analysis

โœ Scribed by Tieng K. Yap Ph.D., Ophir Frieder Ph.D., Robert L. Martino Ph.D. (auth.)


Publisher
Springer US
Year
1996
Tongue
English
Leaves
218
Edition
1
Category
Library

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โœฆ Synopsis


High Performance Computational Methods for Biological SequenceAnalysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field.
This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes.
High Performance Computational Methods for Biological SequenceAnalysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses.

โœฆ Table of Contents


Front Matter....Pages i-xix
Introduction....Pages 1-13
Biological Background....Pages 15-49
Sequence Analysis Algorithms....Pages 51-97
High Performance Computing Architectures and Techniques....Pages 99-109
Multiprocessor Sequence Alignment....Pages 111-141
Multiprocessor Sequence Similarity Searching....Pages 143-157
Biological Sequence Resources on the Internet....Pages 159-189
Looking to the Future....Pages 191-193
Back Matter....Pages 195-211

โœฆ Subjects


Theory of Computation; Human Genetics; Mathematical and Computational Biology; Processor Architectures


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