The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More th
High Performance Computational Methods for Biological Sequence Analysis
โ Scribed by Tieng K. Yap Ph.D., Ophir Frieder Ph.D., Robert L. Martino Ph.D. (auth.)
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Leaves
- 218
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
High Performance Computational Methods for Biological SequenceAnalysis presents biological sequence analysis using an interdisciplinary approach that integrates biological, mathematical and computational concepts. These concepts are presented so that computer scientists and biomedical scientists can obtain the necessary background for developing better algorithms and applying parallel computational methods. This book will enable both groups to develop the depth of knowledge needed to work in this interdisciplinary field.
This work focuses on high performance computational approaches that are used to perform computationally intensive biological sequence analysis tasks: pairwise sequence comparison, multiple sequence alignment, and sequence similarity searching in large databases. These computational methods are becoming increasingly important to the molecular biology community allowing researchers to explore the increasingly large amounts of sequence data generated by the Human Genome Project and other related biological projects. The approaches presented by the authors are state-of-the-art and show how to reduce analysis times significantly, sometimes from days to minutes.
High Performance Computational Methods for Biological SequenceAnalysis is tremendously important to biomedical science students and researchers who are interested in applying sequence analyses to their studies, and to computational science students and researchers who are interested in applying new computational approaches to biological sequence analyses.
โฆ Table of Contents
Front Matter....Pages i-xix
Introduction....Pages 1-13
Biological Background....Pages 15-49
Sequence Analysis Algorithms....Pages 51-97
High Performance Computing Architectures and Techniques....Pages 99-109
Multiprocessor Sequence Alignment....Pages 111-141
Multiprocessor Sequence Similarity Searching....Pages 143-157
Biological Sequence Resources on the Internet....Pages 159-189
Looking to the Future....Pages 191-193
Back Matter....Pages 195-211
โฆ Subjects
Theory of Computation; Human Genetics; Mathematical and Computational Biology; Processor Architectures
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