## Abstract ## Purpose To evaluate the magnetic properties of the spleen in chronically transfused, ironβoverloaded patients with sickle cell disease (SCD) and thalassemia major (TM) and to compare splenic iron burdens to those in the liver, heart, pancreas, and kidneys. ## Materials and Methods
β¦ LIBER β¦
High nontransferrin bound iron levels and heart disease in thalassemia major
β Scribed by Antonio Piga; Filomena Longo; Lorena Duca; Simona Roggero; Tiziana Vinciguerra; Roberto Calabrese; Chaim Hershko; Maria Domenica Cappellini
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 101 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0361-8609
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Objective. Patients with rheumatoid arthritis (RA) have excess morbidity and mortality due to ischemic heart disease. It has been suggested that high serum levels of mannose-binding lectin (MBL) and agalactosyl IgG (IgG-G0) are associated with increased inflammation in RA. MBL also enhances inflamma