High neuron specific enolase levels in bronchoalveolar lavage fluid of patients with lung carcinoma: Diagnostic value, relation to serum neuron specific enolase, and staging

✍ Scribed by Afshin Dowlati; Thierry Bury; Jean Louis Corhay; Thierry Weber; Pedro Mendes; Maurice Radermecker

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 463 KB
• Volume: 77
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19960515)77:10<2039::aid-cncr11>3.0.co;2-w

✦ Synopsis

BACKGROUND.

High levels of neuron specific enolase (NSE) have recently been described in the bronchoalveolar lavage (BAL) fluid of patients with lung carcinoma. Although its value in serum has been extensively studied, its diagnostic value in BAL fluid in terms of sensitivity, specificity, and predictive value have not been evaluated. In addition, its value in staging and relation to serum NSE are yet unknown.