High-affinity binding of two molecules o
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Boris Turk; Veronika Stoka; Ingemar Björk; Christian Boudier; Gunnar Johansson;
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Article
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1995
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Cold Spring Harbor Laboratory Press
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English
⚖ 717 KB
Human low-molecular-weight kininogen (LK) was shown by fluorescence titration to bind two molecules of cathepsins L and S and papain with high affinity. By contrast, binding of a second molecule of cathepsin H was much weaker. The 2:1 binding stoichiometry was confirmed by titration monitored by los