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High levels of glutathione attained during postnatal development of rat testis

✍ Scribed by Calvin, Harold I. ;Turner, Sheila I.

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
362 KB
Volume
219
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

The concentration of glutathione (GSH) in rat testis increases approximately 3‐fold between 8 and 29 days of age, coinciding with the initial wave of meiosis, and is then maintained during spermiogenesis. In the adult rat, mM tissue GSH concentrations rank approximately as follows: liver > testis = kidney > caput epididymidis. However, with respect to protein content, relative GSH levels are testis = liver > kidney. In addition to its possible role during meiosis, the high concentration of GSH attained by developing germinal epithelium may be necessary for the biosynthesis and processing of sperm proteins containing SH and SeH.

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