We have developed a novel, fully automatic method for aligning the three-dimensional structures of two proteins. The basic approach is to first align the proteins' secondary structure elements and then extend the alignment to include any equivalent residues found in loops or turns. The initial secon
High-level synthesis using a genetic algorithm
โ Scribed by Kenji Ohmori
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 186 KB
- Volume
- 83
- Category
- Article
- ISSN
- 1042-0967
No coin nor oath required. For personal study only.
โฆ Synopsis
This paper proposes high-level synthesis using a genetic algorithm that can realize register transfer level circuits from behavioral descriptions. Until now this type of synthesis problem has been separated into scheduling and allocation problems, and the two problems have been solved separately. This procedure has a difficulty that the process may easily fall into a local solution.This paper proposes a simultaneous solution of those problems, so that a circuit better than in the conventional algorithm can be synthesized. The proposed approach, on the other hand, has the disadvantage that the computation time tends to be longer, since the length of the chromosome is increased. To avoid this difficulty, several measures are used such as modification of a faulty gene and discrimination among circuits requiring the same number of resources. A result better than in the conventional approach is obtained for the benchmark problem.
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