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High-level secretion of growth hormone by retrovirally transduced primary human keratinocytes

✍ Scribed by Cibele Nunes Peroni; Cláudia Regina Cecchi; Renata Damiani; Carlos R. J. Soares; Maria Teresa C. P. Ribela; Rosângela do Rocio Arkaten; Paolo Bartolini

Book ID
111640569
Publisher
Humana Press Inc
Year
2006
Tongue
English
Weight
181 KB
Volume
34
Category
Article
ISSN
1073-6085

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Secretion of mouse growth hormone by transduced primary human keratinocytes: prospects for an animal model of cutaneous gene therapy
✍ Cibele Nunes Peroni; Cláudia Regina Cecchi; Cristiane Wanderley Rosauro; Suely N 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 585 KB

## Abstract ## Background Keratinocytes are a very attractive vehicle for __ex vivo__ gene transfer and systemic delivery because proteins secreted by these cells may reach the circulation via a mechanism that mimics the natural process. ## Methods An efficient retroviral vector (LXSN) encoding