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High-level regulated expression of the human G6PD gene in transgenic mice

✍ Scribed by Colm M. Corcoran; Peter Fraser; Giuseppe Martini; Lucio Luzzatto; Philip J. Mason

Book ID
116133585
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
961 KB
Volume
173
Category
Article
ISSN
0378-1119

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To analyze the regulation of human serum amyloid P component (SAP) gene expression, we have produced seven transgenic mice. The 3.3 kb human SAP genes containing about 0.8 kb of 5' and 1.5 kb of 3' flanking region were injected into fertilized eggs of C57BL/6 mice. In five of the seven transgenic mi