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High Level of Notch1 Protein is Associated with Poor Overall Survival in Colorectal Cancer

✍ Scribed by Dake Chu; Yunming Li; Weizhong Wang; Qingchuan Zhao; Jipeng Li; Yuanyuan Lu; Mengbin Li; Guanglong Dong; Hongwei Zhang; Huahong Xie; Gang Ji


Book ID
111773425
Publisher
Springer
Year
2010
Tongue
English
Weight
239 KB
Volume
17
Category
Article
ISSN
1068-9265

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## Abstract The PI3K‐AKT pathway is activated in a variety of human cancers, resulting in disturbance of cell growth, proliferation and survival. Among the factors affecting the pathway, the __K‐Ras__ mutation and __PIK3CA__ mutation are the most common oncogenic alterations in colorectal cancer. W