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High-level expression of functional recombinant human coagulation factor VII in insect cells

✍ Scribed by Nasser Masroori; Raheleh Halabian; Mahshid Mohammadipour; Amaneh Mohammadi Roushandeh; Mahdi Rouhbakhsh; Ali Jahanian Najafabadi; Mahdi Edalati Fathabad; Mohamad Salimi; Mohamad Ali Shokrgozar; Mehryar Habibi Roudkenar


Publisher
Springer Netherlands
Year
2010
Tongue
English
Weight
224 KB
Volume
32
Category
Article
ISSN
0141-5492

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In order to develop an efficient process for large-scale production of recombinant protein, various factors were studied which affect the productivity of Sf-9 (Spodoptera frugiperda) insect cells when using the baculovirus expression system. It was shown that upon infection with the Bac-BRV6L recomb