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High-Level Expression of Antimicrobial Peptide Mediated by a Fusion Partner Reinforcing Formation of Inclusion Bodies

✍ Scribed by J.H. Lee; J.H. Kim; S.W. Hwang; W.J. Lee; H.K. Yoon; H.S. Lee; S.S. Hong

Book ID: 115586792
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 142 KB
Volume: 277
Category: Article
ISSN: 0006-291X
DOI: 10.1006/bbrc.2000.3712

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## Abstract A method is presented that allows efficient production of antimicrobial peptides in bacteria by means of fusion to the histone fold domain of the human transcription factor TAF12. This small fusion partner drives high‐level expression of peptides and leads to their accumulation in an en