High-level expression and secondary structure analysis of the bovine mature prion protein
β Scribed by Dawei Wang; Huaiyi Yang; Zihe Rao; Bo Tian
- Book ID
- 105727101
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 432 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1001-6538
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## Summary Twentyβfour microsatellite sites with at least three repeats were found in the bovine prion protein gene (__PRNP__) and 23 in the ovine __PRNP__ gene. Eight microsatellite sites were polymorphic in cattle and six in sheep with up to 10 alleles per site. In many cases allelic DNA fragment
The prion protein (PrP), encoded by a chromosomal gene, is associated with development of the neurodegeneration of prion-induced diseases. Since determination of the complete structure of the gene encoding PrP is important for understanding gene expression in the central nervous system (CNS), the nu