High incidence of the silent allele at cholinesterase locus I in Vysyas of Andhra Pradesh (S. India)

✍ Scribed by P. R. Rao; K. B. Gopalam

• Book ID: 104704527
• Publisher: Springer
• Year: 1979
• Tongue: English
• Weight: 158 KB
• Volume: 52
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00284608

✦ Synopsis

Four-hundred and ninety individuals belonging to the Vysya caste from Andhra Pradesh were screened for pseudocholinesterase variants at the E1 and E2 locus. A high incidence of the silent allele (gene frequency=0.1112) was recorded with homozygotes exceeding 2% of the population. Dibucaine- and fluoride-resistant alleles were found in a heterozygous form with the usual alleles in four individuals each. No C5+ variant at the E2 locus was found.