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High incidence of asymptomatic urogenital infection in patients with uveitis anterior

✍ Scribed by W. Graninger; E. Arocker-Mettinger; H. Kiener; A. Benke; J. Szöts-Sötz; R. Knobler; J. Smolen

Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
327 KB
Volume
82
Category
Article
ISSN
0012-4486

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✦ Synopsis

Acute anterior uveitis (AAU) may be associated with systemic infectious or inflammatory disease. We examined 92 patients with the first attack of acute anterior uveitis; all patients were free of any extraocular symptoms. A thorough clinical examination did not reveal any systemic underlying disease. In the course of microbiological examination, however, a high incidence of asymptomatic infection of the urethra and/or cervix with ureaplasma urealyticum, chlamydia trachomatis and mycoplasma hominis was found. Infections with ureaplasma were significantly more frequent in patients with AAU when compared with a sex-and age-matched control group. There was no statistically valid association of these infections with the HLA-B27 phenotype in the patients. The higher rate of urogenital infections in patients with AAU may reflect a higher rate of sexual promiscuity. Transmission of infectious agents seems to be one possible factor in the pathogenesis of AAU.

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