High-grade prostatic intraepithelial neoplasia and prostate cancer risk reduction
β Scribed by Mitchell S. Steiner
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 200 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0724-4983
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## Abstract Highβgrade prostatic intraepithelial neoplasia (HGPIN) appears to represent an ideal target for chemoprevention of prostate cancer (PCa). HGPIN responds to androgen ablation and has prostate stem cell antigen (PSCA) mRNA expression. One hundred and seventy two patients with isolated HGP
## Abstract In this study, we used 7 informative microsatellite markers at 8p22, 23.1, and 23.2 in Japanese patients to compare frequency of loss of heterozygosity (LOH) in 53 lesions of highβgrade prostatic intraepithelial neoplasia (HGPIN), 38 cases (38 lesions) of incidental prostate cancer (IPC