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High-grade neuroendocrine carcinoma of the lung shows increased thymidylate synthase expression compared to other histotypes

โœ Scribed by Takashi Ibe; Kimihiro Shimizu; Tetsuhiro Nakano; Seiichi Kakegawa; Mitsuhiro Kamiyoshihara; Takashi Nakajima; Kyoichi Kaira; Izumi Takeyoshi

Book ID
102440215
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
311 KB
Volume
102
Category
Article
ISSN
0022-4790

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โœ Paolo Ceppi; Marco Volante; Silvia Saviozzi; Ida Rapa; Silvia Novello; Alberto C ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 278 KB ๐Ÿ‘ 1 views

## Abstract ## BACKGROUND. In patients with cancer, one of the main mechanism of resistance to antimetabolite drugs is related to higher levels of thymidylate synthase (__TS__) activity. ## METHODS. To investigate the association between __TS__ expression and histopathologic data, 56 resection s