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High glucose potentiates mitogenic responses of cultured ovine coronary smooth muscle cells to platelet derived growth factor and transforming growth factor-β1

✍ Scribed by Peter J. Little; Terri J. Allen; Kazuhiko Hashimura; Julie Nigro; Caroline A. Farrelly; Rodney J. Dilley


Book ID
117370607
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
186 KB
Volume
59
Category
Article
ISSN
0168-8227

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We have examined the ability of transforming growth factor-pl (TGF-p1) and platelet-derived growth factor-BB (PDGF-BB) to regulate the expression of various integrins in cultured rabbit vascular smooth muscle cells (SMC). We found that expression of the a,p3 integrin complex was induced by both grow