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High glucose enhances inducible nitric oxide synthase expression. Role of protein kinase C-βII

✍ Scribed by María E. Pacheco; Amada Beltrán; Juliana Redondo; Ana M. Manso; María J. Alonso; Mercedes Salaices


Book ID
113586111
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
441 KB
Volume
538
Category
Article
ISSN
0014-2999

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## Abstract Expression of inducible nitric oxide synthase (iNOS), which leads to the production of nitric oxide (NO), is stimulated by proinflammatory cytokines such as interleukin‐1β (IL‐1β) and tumor necrosis factor‐α (TNF‐α). Here we report on the roles of nuclear factor‐κB (NF‐κB) and mitogen‐a