High frequency of triplicated α-globin loci and absence or low frequency of α thalassemia in Polynesian Samoans

High frequency of deletional α-thalassem

High frequency of deletional α-thalassemia in β-thalassemia trait: Implications for genetic counseling

✍ I. Panigrahi; P.H. Ahmed Rafeeq; V.P. Choudhry; R. Saxena 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 73 KB 👁 1 views

## Abstract Thalassemias are a group of genetic hemolytic disorders with varying phenotypes. In this study, the frequency of α globin gene deletions was studied in the β‐thalassemia trait, the mildest form of the disorder. Eleven out of 33 (33%) individuals were positive for α^−3.7 kb^ deletions. N