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High frequency of the MAGE-1 gene expression in hepatocellular carcinoma

โœ Scribed by N Yamashita; H Ishibashi; K Hayashida; J Kudo; K Takenaka; K Itoh; Y Niho

Book ID
118686493
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
795 KB
Volume
24
Category
Article
ISSN
0270-9139

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High frequency of the MAGE-1 gene expres
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ized in a human melanoma cell line (MZ2-MEL). 4 Expression The MAGE-1 gene, originally isolated from a human of the MAGE-1 gene on HLA-A1 positive tumor cells directs melanoma cell line, directs the expression of a potential the expression of a nonapeptide that allows specific recognitumor-rejection

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## BACKGROUND. The 12 members of the MAGE gene family encode tumor specific antigens that are recognized by autologous cytotoxic T lymphocytes (CTL). The MAGE genes are expressed not only in melanoma but in the other malignant tumors as well. There is, however, little information on their expressi