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High frequency of the 844ins68 cystathionine-β-synthase gene variant in Down syndrome children with acute myeloid leukemia

✍ Scribed by Ge, Y; Jensen, T; James, S J; Becton, D L; Massey, G V; Weinstein, H J; Ravindranath, Y; Matherly, L H; Taub, J W


Book ID
110055260
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
114 KB
Volume
16
Category
Article
ISSN
0887-6924

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## Abstract Previous cytogenetic studies of myeloid and acute lymphoblastic leukemias in children with Down syndrome (ML‐DS and DS‐ALL) have revealed significant differences in abnormality patterns between such cases and acute leukemias in general. Also, certain molecular genetic aberrations charac