During the past years, significant advances have been made in our understanding of the development of the human brain, and much of this knowledge comes from genetic studies of disorders associated with abnormal brain development. We employed array-comparative genomic hybridization (CGH) to investiga
✦ LIBER ✦
High frequency of neurexin 1β signal peptide structural variants in patients with autism
✍ Scribed by Jinong Feng; Richard Schroer; Jin Yan; Wenjia Song; Chunmei Yang; Anke Bockholt; Edwin H. Cook Jr.; Cindy Skinner; Charles E. Schwartz; Steve S. Sommer
- Book ID
- 115543573
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 110 KB
- Volume
- 409
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Latent membrane protein 1 (LMP‐1) is an Epstein‐Barr virus‐encoded oncoprotein expressed in ∼50–70% of nasopharyngeal carcinoma (NPC). Previous studies have shown that NPC‐derived LMP‐1 variants carrying 30 bp deletion and specific mutations in the 3′C‐terminal region confer high oncoge