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High frequency of allelic imbalance at regions of chromosome arm 8p in ovarian carcinoma

โœ Scribed by Ingrid Pribill; Paul Speiser; Jennifer Leary; Sepp Leodolter; Neville F Hacker; Michael L Friedlander; Daniel Birnbaum; Robert Zeillinger; Michael Krainer


Book ID
114135091
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
979 KB
Volume
129
Category
Article
ISSN
0165-4608

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Deletions on chromosome arm 8p, as defined by allelic imbalance, are a frequent event in many different types of malignant tumors, including those of the head and neck. These regions are thought to harbor tumor suppressor genes. In order to define a high-density deletion map of this chromosomal arm