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High field localized proton spectroscopy in small volumes: greatly improved localization and shimming using shielded strong gradients

✍ Scribed by Peter C. M. van Zijl; Chrit T. W. Moonen; Jeffry R. Alger; Jack S. Cohen; Scott A. Chesnick


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
565 KB
Volume
10
Category
Article
ISSN
0740-3194

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✦ Synopsis


The availability of shielded gradients facilitates accurate single-voxel spectroscopy. Exact localization (90-99%) of volumes as small as 2 x 2 x 2 mm is demonstrated using a modified stimulated echo sequence. Strong gradient pulses (up to 200 mT/m) are employed to clear the stimulated echo of unwanted magnetization, enabling superior (single-scan) shimming of the selected volume. In vivo and in vitro proton NMR results at 4.7 T are presented.