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High Extracellular Calcium Inhibits Osteoclast-like Cell Formation by Directly Acting on the Calcium-Sensing Receptor Existing in Osteoclast Precursor Cells

✍ Scribed by Masanori Kanatani; Toshitsugu Sugimoto; Michiko Kanzawa; Shozo Yano; Kazuo Chihara


Book ID
115584037
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
142 KB
Volume
261
Category
Article
ISSN
0006-291X

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High extracellular calcium stimulates os
✍ Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; Kazuo Chihara 📂 Article 📅 2009 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 827 KB

## Abstract The present study was performed to examine the effect of the high concentration of extracellular calcium ([Ca^2+^]~e~) on osteoclast‐like cell formation and bone‐resorbing activity in the presence or absence of osteoblasts. High [Ca^2+^]~e~ (3 and 5 mM) significantly stimulated osteocla