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High expression of Cyp6g1, a cytochrome P450 gene, does not necessarily confer DDT resistance in Drosophila melanogaster

✍ Scribed by Srilalitha Kuruganti; Vita Lam; Xuguo Zhou; Gary Bennett; Barry R. Pittendrigh; Ranjan Ganguly

Book ID: 116507686
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 520 KB
Volume: 388
Category: Article
ISSN: 0378-1119
DOI: 10.1016/j.gene.2006.09.019

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## Abstract Cytochrome P450 monooxygenase CYP6G1 of __Drosophila melanogaster__ was heterologously expressed in a cell suspension culture of __Nicotiana tabacum.__ This __in vitro__ system was used to study the capability of CYP6G1 to metabolize the insecticide methoxychlor (=1,1,1‐trichloro‐2,2‐bi