Efficient ablation by immunotoxin-mediat
โ
Tomoko Kobayashi; Yukiko Kida; Takeshi Kaneko; Ira Pastan; Kazuto Kobayashi
๐
Article
๐
2001
๐
John Wiley and Sons
๐
English
โ 164 KB
## Background: Immunotoxin-mediated cell targeting (imct) is a technique for conditional genetic ablation of specific cell types. imct provides a useful approach for generating animal models for human neurodegenerative disorders. the strategy of imct depends on the cytotoxic activity of antitac-bas